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The relationship between cerebrospinal fluid C-reactive protein and neonatal meningitis

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Original Article

Tehran Univ Med J (TUMJ) 2014 February;71(11):2??-?

Author Affiliations:
Nastaran Khosravi M.D.1
Nasrin Khalesi M.D.2
Samileh Noorbakhsh M.D.1
Shima Javadinia M.D.3
Ramin Asgarian M.D.4
Azardokht Tabatabai M.Sc.5*

1- Department of Pediatric Infectious Diseases, Research Center of Pediatric Infectious Diseases, Iran University of Medical Sciences,   Tehran, Iran.
2- Department of Neonatal Diseases, Ali Asghar Hospital, Iran University of Medical Sciences, Tehran, Iran.
3- Department of Internal Medicine, Research Center of Pediatric Infectious Diseases, Iran University of Medical Sciences, Tehran, Iran.
4- Department of Community Medicine, Research Center of Pediatric Infectious Diseases, Iran University of Medical Sciences, Tehran, Iran.
5- Faculty Member, Research Center of Pediatric Infectious Diseases, Iran University of Medical Sciences, Tehran, Iran.

* Corresponding author: Research Center for Pediatric Infectious Diseases, Hazrat-e-Rasool Akram Hospital, Niayesh St., Sattarkhan Ave., Tehran, Iran.
Tel: +98-21-66504994
E-mail: cpidir@gmail.com

Received: 31 Aug. 2013    Accepted: 16 Nov. 2013    Available online: 01 Jan. 2014

Abstract:
Background: Meningitis is one of the serious and dangerous infections in the infancy and childhood and rapid diagnosis of meningococcal disease is important, especially in infants. C-reactive protein (CRP) is a protein found in blood and is an acute phase protein. CRP sensitive reactive that used for diagnosis of infection. This study conducted to assessment of the relationship between cerebrospinal fluid C-reactive protein, and neonatal meningitis, as well as diagnostic value of test. (more…)


Femoral malrotation following intramedullary nailing in 70 patients

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Original Article

Tehran Univ Med J (TUMJ) 2014 February;71(11):718-22

Author Affiliations:
Sadegh Saberi M.D.1
Amir Sobhani Eraghi M.D.2*
Mahmood Farzan M.D.1
Hossein Safar-Ali Farkhani M.D.3
Shirin Mardookhpour M.D.4
Mahmood Mirzaaghapour M.D.2

1- Department of Orthopaedic Surgery, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.
2- Department of Orthopaedics, Rasoul Akram Hospital, Tehran University of Medical Sciences, Tehran, Iran.
3- Department of Orthopaedic Surgery, Zahedan University of Medical Sciences, Zahedan, Iran.
4- Department of Radiology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.

* Corresponding author: Rasoul Akram Hospital, Niayesh St., Sattarkhan St., Tehran, Iran.
Tel: +98-21-64352264
E-mail: amir_sobhany@yahoo.com

Received: 27 Jun. 2013    Accepted: 04 Nov. 2013    Available online: 01 Jan. 2014

Abstract:
Background: Rotational deformity after intramedullary nailing is a well-known complication. Femoral malrotation is the most common form of malunion but it is underrecognized in part because of the difficulty in accurately assessing rotation as well as the variation that exists in normal anatomy. The aim of this study was to evaluate femoral malrotation following intramedullary nailing of the femur. (more…)


Distal femoral varus osteotomy in 27 young patients with genu valgum

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Original Article

Tehran Univ Med J (TUMJ) 2014 February;71(11):713-7

Author Affiliations:
Mahmoud Jabalameli M.D.1
Abolfazl Bagheri Fard M.D.1
Ali Jahansouz M.D.1*
Tahmineh Mokhtari Ph.D.2

1- Department of Orthopedic Surgery, Shafa Orthopedic Hospital, Iran University of Medical Sciences, Tehran, Iran.
2- Ph.D. Student of Anatomy, Tehran University of Medical Sci-ences, Tehran, Iran.

* Corresponding author: Shafa Orthope-dic Hospital, Mojahedin St., Baharestan, Tehran, Iran.
Tel: +98-21-33542022
E-mail: a_jahansouz@yahoo.com

Received: 08 Oct. 2013    Accepted: 16 Nov. 2013    Available online: 01 Jan. 2014

Abstract:
Background: Genu valgum deformity is exaggerated valgus alignment of lower ex-tremity mechanical axis in knee with a joint line that slopes superolaterally and is cor-rected by distal femoral osteotomy. In this study the results of treatment and satisfaction in patients with genu valgum were evaluated according to knee society score (KSS) and changes in pre-operation and post-operation lower extremity mechanical axis were compared to each other. (more…)


Delivered dose to scrotum in rectal cancer radiotherapy by thermolumi-nescence dosimetry comparing to dose calculated by planning software

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Original Article

Tehran Univ Med J (TUMJ) 2014 February;71(11):707-12

Author Affiliations:
Peiman Haddad M.D.1*
Zhaleh Karimimoghaddam M.D.1
Farshid Farhan Ph.D.1
Mahbod Esfahani M.D.2
Mahdieh Afkhami Ph.D.2
Farnaz Amouzegar-Hashemi M.D.1

1- Department of Radiation Oncology, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran.
2- Department of Radiation Physics, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran.

* Corresponding author: Department of Radiation Oncology, Cancer Institute, Imam-Khomeini Hospital, Keshavarz Blvd., Tehran, Iran.
Tel.: +98-21-66948672
E-mail: haddad@tums.ac.ir

Received: 21 Jun. 2013    Accepted: 19 Oct. 2013    Available online: 01 Jan. 2014

Abstract:
Background: Colorectal carcinoma is a common malignancy, in treatment of which pelvic radiotherapy plays an important role. But this may lead to azospermia. We de-signed a study to determine the delivered dose to the testis with thermoluminescence dosimetry (TLD) and compare it to the dose calculated by the Three-dimensional plan-ning software. (more…)


Letrozole and misoprostol versus misoprostol alone for termination of pregnancy: a randomized clinical trial

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Original Article

Tehran Univ Med J (TUMJ) 2014 February;71(11):700-6

Author Affiliations:
Zahra Rezai M.D.1
Seydeh Sareh Heydari Bazardehi M.D.1*
Azizeh Ghasemi Nezhad M.D.1
Amir Saeid Sadeghi M.D.2
Batool Ghorbani Yekta Ph.D.3

1- Department of Gynecology, School of Medicine, Tehran  Uni-versity of Medical Sciences, Tehran, Iran.
2- Department of Gastroenterology, School of Medicine, Shahid Beheshti University of Medical   Sciences, Tehran, Iran.
3- Medical Sciences Research   Center, Islamic Azad University, Tehran Medical Branch, Tehran, Iran

* Corresponding author: Zanan Hospital, Karimkhan Zand St., North Nejatollahi St., Tehran, Iran.
Tel: +98-21-88900002
E-mail: sshb79@yahoo.com

Received: 27 Apr. 2013    Accepted: 19 Oct. 2013    Available online: 01 Jan. 2014

Abstract:
Background: To compare the success rate and side effects of letrozole and misoprostol versus misoprostol alone for medical termination of early pregnancy. (more…)


Utilization of Lambda bacteriophage as an Apoptin effective delivery platform to the BT-474 human breast carcinoma

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Original Article

Tehran Univ Med J (TUMJ) 2014 February;71(11):691-9

Author Affiliations:
Narmin Ghaderi M.Sc.1*
Khosro Esazadeh Ph.D.1
Alireza Shoae Hasani Ph.D.2

1- Department of Microbiology, Faculty of Science, Islamic Azad University Lahijan Branch, Gilan, Iran.
2- Department of Stem Cell and Tissue Engineering, Research Center for Science and Technology in Medicine, Tehran University of Medical Sciences, Tehran, Iran.

* Corresponding author: No. 3, Edalat St, Yasaman Sq., Daneshjoo Blvd., Velenjak, Tehran, Iran.
Tel: +98-21-22416141
E-mail: narminghaderi@yahoo.com

Received: 28 May. 2013    Accepted: 04 Nov. 2013    Available online: 01 Jan. 2014

Abstract:
Background: Apoptin is a protein from chicken anemia virus that could induce apoptosis specifically in the cancer cells but it has not any effect in the normal cells. Phage therapy is a novel field of cancer therapy and phage nanobioparticles (NBPs) such as λ phage could be modified to deliver and express genetic cassettes into eukaryotic cells safely in contrast with animal viruses. The bacteriophages like Lambda could be manipulated to deliver genetic cassettes into eukaryotic cells and express the gene safely. We developed the safe way for the expression of Apoptin gene via Lambda bacteriophage in the human tumors. (more…)


Table of Contents >> Tehran University Medical Journal (TUMJ), Volume 71, Number 10, January 2014

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A review of bone metastasis and its treatments, with a special emphasis on local and systemic radiotherapy
Haddad P, Maddah Safaei A, Fard Esfahani A.

The effect of oral Matricaria Chamomilla extract and selenium on postpartum depression and plasma oxidant-antioxidant system in mice
Harati E, Sadeghipour Roodsari H.R, Seifi B, Kamalinejad M, Nikseresht S.

A new grading system “two-tier” in classification of ovarian serous carcinoma and evaluation of P53 gene expression by immunohistochemical staining
Izadi-Mood N, Sarmadi S, Rajabian B, Yarandi F, Rajabiani A.

Evaluation of recurrent colorectal carcinoma after curative resection
Keshvari A, Fazeli M.S, Kazemeini A, Meysamie A, NouriTaromlou M.K.

Comparison of two nosocomial infection surveillance in a neonatal ward
Abedini M, Ghotbi N, Hadavi N, Chavoshi D, Asgharian N.

Serological study of Helicobacter pylori infection in patients with Polycystic Ovary Syndrome
Sohrabvand F, Shariat M, Farahvash M.J, Haghollahi F, Khosravi M, Maasomi M, Bagheri M, Abdollahi A, Sarbiyaie A, Bashari F.

Efficacy of education with American Society of Health system Pharmacists guidelines on the prevention of stress ulcer
Gharebaghi N, Valizade Hasanloei M.A, Adeli S.H, Mansuri Zangir S.A, Rasuli J.

The effect of massage therapy on weight gain and calories intake in premature neonates: a brief report
Amini E, Ebrahim B, Dehghan P, Fallahi M, Sedghi S, Amini F, Shariat M.

A large gastrointestinal stromal tumor of duodenum: a case report
Ahmadi Amoli H, Akhlaghi A, Ramim T.

Dyskeratosis congenita: a case report
Mirnezami M, Pakbaz B, Saidinejad Z.


Dyskeratosis congenita: a case repot

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Case Report

Tehran Univ Med J (TUMJ) 2014 January;71(10):685-9

Author Affiliations:
Mina Mirnezami Ph.D.1
Behfar Pakbaz M.D.2*
Zeinab Saidinejad M.D.3

1- Department of Dermatologist, Vali-e-Asr Hospital, Arak University of Medical Sciences, Arak, Iran.
2- Department of Internal Medicine, Amiralmomenin Hospital, Arak University of Medical Sciences, Arak, Iran.
3- Department of Infectious Disease, Vali-e-Asr Hospital, Arak University of Medical Sciences, Arak, Iran.

*Corresponding author: Amiralmomenin Hospital, Sardasht Basij Sq., Arak, Iran.
Tel: +98- 86-34173601-9
E-mail: behfar.pakbaz@yahoo.com

Received: 19 May 2013    Accepted: 14 Sep. 2013    Available online: 01 Dec. 2013

Abstract:
Background: Dyskeratosis Congenita (DC) is a rare inherited disease with an incidence of approximately one case per million population. The disease is characterized by a classic triad: nail changes, color reticulated skin and oral leukoplakia. In these patients, premature death is often associated with bone marrow failure, infections, pulmonary complications, or malignancy. Three patterns of inheritance for dyskeratosis congenita have been reports, X-linked recessive trait, autosomal dominant and recessive trait. The present study is a case report of an adoloscent patient with dyskeratosis congenita. (more…)


A large gastrointestinal stromal tumor of duodenum: a case report

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Case Report

Tehran Univ Med J (TUMJ) 2014 January;71(10):679-84

Author Affiliations:
Hadi Ahmadi Amoli M.D.1
Ali Akhlaghi M.D.1
Tayeb Ramim M.D.2*

1- Department of Surgery, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran.
2- Sina Trauma and Surgery Research Center, Tehran University of Medical Sciences, Tehran, Iran.

*Corresponding author: Sina Hospital, Hassan Abad Sq., Imam Khomeini Ave., Tehran, Iran.
Tel: +98- 21- 66348529
E-mail: dr.tayebramim@gmail.com

Received: 12 Apr. 2013    Accepted: 07 Sep. 2013    Available online: 01 Dec. 2013

Abstract:
Background: Gastrointestinal stromal tumors are gastrointestinal tract mesenchymal tumors with gene mutations. The most common site of gastrointestinal stromal tumors is in stomach (40-60%) and small intestine (30-40%), and rare cases about 3-5% of them occur in the duodenum. (more…)


The effect of massage therapy on weight gain and calories intake in premature neonates: a brief report

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Brief Report

Tehran Univ Med J (TUMJ) 2014 January;71(10):674-8

Author Affiliations:
Elaheh Amini M.D.1
Bita Ebrahim M.D.2
Paideh Dehghan M.D.3
Mohadeseh Fallahi M.D.3
Samaneh Sedghi M.D.3
Fereshteh Amini M.Sc.4
Mamak Shariat M.D.5*

1- Department of Neonatologisst, Maternal- Fetal & Neonatal Research Center, Tehran University of Medical Sciences, Tehran, Iran.
2- Department of Pediatrician, Maternal- Fetal & Neonatal Research center, Tehran University of Medical Sciences, Tehran, Iran.
3- General Practitioner, Breastfeeding Research Center, Tehran University of Medical Sciences, Tehran, Iran.
4- Midwife, Vali-e-Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran.
5- Department of Maternal & Child Health Specialist, Maternal- Fetal & Neonatal Research Center, Tehran University of Medical Sciences, Tehran, Iran.

*Corresponding author: Maternal, Fetal & Neonatal Research Center, Imam Khomeini Hospital, Vali-e-Asr Hospital, Keshavarz Blvd., Tehran, Iran.
Tel: +98- 21- 66591316
E-mail: mshariat@tums.ac.ir

Received: 11 Apr. 2013    Accepted: 22 May 2013    Available online: 01 Dec. 2013

Abstract:
Background: Improvement of growth, nutrition and calories intake in neonates is derived by massage.
Methods: This study is a randomized clinical trials settled in Vali-e-Asr Hospital Neonatal Intensive Care Unit (NICU) ward in 2012. The control group consisted of 19 infants who were not massaged on them. 15 infants in the intervention group received massage therapy for 10 days, three times a day by trained massage theurapist. Massage last 15 minutes and was done one hour after feeding. Massages were done in 2-7 days neonates. Weight gain, intake calories and oral feeding were compared between studied groups. Data was registered in SPSS v.18 and was analyzed via compatible statistics tests. (more…)