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Incomplete molar pregnancy with live coexisting fetus: a case report

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Case Report

Tehran Univ Med J (TUMJ) 2014 March;71(12):821-4

Author Affiliations:
Leila Pourali M.D.1
Sedigheh Ayati M.D.1
Fatemeh Vahidroodsari M.D.1* Manizhe Javanmard M.D.1
Faezeh Poursadrollah2

1- Department of Gynecology and Obstetrics, Ghaem Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
2- Student of Medicine, Iran Uni-versity of Medical Sciences, Tehran, Iran.

*Corresponding author: Department of Gynecology and Obstetrics, Faculty of Medicine, Mashhad University of Medi-cal Sciences, Ghaem Hospital, Ahmada-bad St., Mashhad, Iran.
Tel: +98- 511-8412477
E-mail: vahidroodsarif@mums.ac.ir

Received: 27 Aug. 2013    Accepted: 18 Nov. 2013    Available online: 01 Feb. 2014

Abstract:
Background: Twin pregnancy with a fetus and a diploid complete mole is not rare, but, the cases of twin pregnancy with a partial mole are rare. Nowadays, the prevalence of these cases has been increased due to the high rate of assisted reproductive techniques in reproductive medicine. The importance of twin pregnancy with a fetus and a diploid complete mole is mainly due to systemic complications such as hypertension and maternal hemorrhage and the possibility of trophoblastic tumor following delivery. Different studies have reported some results about similar cases, but limited case reports are presented in our country. The aim of this study is to report a case with incomplete molar pregnancy concomitant with a live fetus. (more…)


Comparative study on the effect of fish-oil derived docosahexaenoic and ecosapantaenoic acid on proliferation of colorectal cancer cell line: a breif report

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Brief Report

Tehran Univ Med J (TUMJ) 2014 March;71(12):816-20

Author Affiliations:
Parinaz Ahangar M.Sc.1, 2 Mo-hammad Reza Sam Ph.D.1,2,3*
Vahid Nejati Ph.D.1

1- Department of Histology and Embryology, Faculty of Sciences, Urmia University, Urmia, Iran.
2- Department of Cellular and Molecular Biotechnology, Institute of Biotechnology, Urmia University, Urmia, Iran.
3- Royan Stem Cell Technology Company, West Azerbaijan Cord Blood Bank, Urmia, Iran.

*Corresponding author: Department of Cellular and Molecular Biotechnology, Institute of Biotechnology, Urmia Uni-versity, Shahid Beheshti St., Urmia, Iran.
Tel: +98- 441-3440199
E-mail: m.sam@urmia.ac.ir

Received: 02 July 2013    Accepted: 19 Oct. 2013    Available online: 01 Feb. 2014

Abstract:
Background: In advanced stages, Colorectal cancer remains often refractory to classic therapies. In consequence, search for new therapeutic modalities with minimal toxicity is of particular interest in colon cancer management. In this regard, powerful growth-inhibitory effect has been shown for fish-oil derived Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA) against cancer cells. In the present study, we evaluated the anti-cancer effect of EPA and DHA (n3-polyunsaturated fatty acids, n3-PUFAs) on the human colorectal cancer cell line (LS174T) on a dose-response and time-course basis. (more…)


Outcomes of vaginal delivery and cesarean in Mashhad Ghaem University Hospital

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Original Article

Tehran Univ Med J (TUMJ) 2014 March;71(12):807-15

Author Affiliations:
Hassan Boskabadi M.D.1
Maryam Zakerihamidi Ph.D.
Student.2*
Fatemeh Bagheri M.Sc.3

1- Department of Pediatrics, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
2- Reproductive Health, Depart-ment of Reproductive Health, School of Nursing and Midwifery, Mashhad University of Medical Science, Mashhad, Iran.
3- Department Pediatrics Nursing, School of Nursing and Midwifery, Mashhad Islamic Azad University, Mashhad, Iran.

*Corresponding author: Department of Reproductive Health, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran.
Tel: +98- 511- 8591511
E-mail: maryamzaker-hamidi@yahoo.co.nz

Received: 07 Jun 2013    Accepted: 07 Dec. 2013    Available online: 01 Feb. 2014

Abstract:
Background: Normal vaginal delivery is the best method of delivery. Vaginal delivery is followed by the best pregnancy outcomes. Reducing the rate of cesarean delivery has been a health goal for the United States with economic and social advantages. This study has been conducted with aim of maternal and neonatal outcomes of Normal Vaginal Delivery (NVD) and comparing with cesarean delivery. (more…)


Prophylactic dialysis in non-dialysis-dependent patients with renal failure after CABG

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Original Article

Tehran Univ Med J (TUMJ) 2014 March;71(12):800-6

Author Affiliations:
Roghayyeh Borji M.D.1
Mohammad Reza Khatami M.D.2*
Mohammad Reza Abbasi M.D.2
Alipasha Meysamie M.D.3
Khosro Barkhordari M.D.4
Farah Ayatollah Esfahani5
Mina Pashang5
Laleh Ghadirian M.D.6

1- Department of Internal Medicine, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.
2- Department of Nephrology, Nephrology Research Center, Imam Khomeini hospital, Tehran University of Medical Sciences, Tehran, Iran.
3- Department of Community Community Medicine, Tehran University of Medical Sciences, Tehran, Iran.
4- Department of Anesthesiology & Critical Care Medicine, Tehran heart center, Tehran University of Medical Sciences, Tehran, Iran.
5- Nurse, Cardiovascular Research Department, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.
6- Community Based Participatory Research Centre, Center for Academic and Health Policy, Tehran University of Medical Sciences, Tehran, Iran.

*Corresponding author: Imam Khomeini Hospital Complex, Keshavarz Blvd., Tehran, Iran.
Tel: +98- 21- 66938081-9
E-mail: khatamis@sina.tums.ac.ir

Received: 21 Sep. 2013    Accepted: 30 Oct. 2013    Available online: 01 Feb. 2014

Abstract:
Background: The mortality due to Coronary Artery Bypass Graft (CABG) in patients with chronic renal failure is more common than normal population. This study evalu-ates the impacts of prophylactic dialysis on decreasing mortality and morbidity of non- dialysis-dependent patients with renal failure after CABG surgery. (more…)


Vitamin A, D and zinc serum levels in children with and without acute respiratory tract infection in two university hospitals

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Original Article

Tehran Univ Med J (TUMJ) 2014 March;71(12):794-9

Author Affiliations:
Shima Javadi-Nia M.D.1
Samileh Noorbakhsh M.D.2
Anahita Izadi M.D.3
Mohammad Reza Shokrollahi M.D.4
Ramin Asgarian M.D.5
Azardokht Tabatabaei M.D.2*

1- Research Center of Pediatric Infectious Diseases, Hazrat-e-Rasoul Akram Hospital, Department of Internal Medicine, Iran University of Medical Sciences, Tehran, Iran.
2- Research Center of Pediatric Infectious Diseases, Hazrat-e-Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
3- Departments of Pediatric Infectious Diseases, Bahrami Hospital, Tehran University of Medical Sciences Tehran, Iran.
4- Departments of Pediatric Infectious Diseases, Ghom University of medical Sciences, Ghom, Iran.
5- Departments of Community Medicine, Research Center of Pediatric Infectious Diseases, Hazrat-e-Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.

*Corresponding author: Research Center of Pediatric Infectious Diseases, Hazrat-e-Rasoul Akram Hospital, Niayesh St., Sattarkhan Ave., Tehran, Iran.
Tel: +98- 21- 66516049
E-mail: cpidir@gmail.com

Received: 21 Oct. 2013    Accepted: 30 Oct. 2013    Available online: 01 Feb. 2014

Abstract:
Background: Severity of respiratory infection in children is depended on various fac-tors such as causative organism and the host immunologic response to the organism. Vitamins and micronutrients play an important role in this response with supporting the immune system and therefore, the response to infections. Nutritional deprivations in children, especially vitamins and micronutrients such as zinc, vitamin A and vitamin D are very common in middle east and other countries in Asia, which is due to inappro-priate diet and nutrient loss in recurrent infections. This study aimed to evaluate the se-rum levels of vitamins A, D and zinc in hospitalized children aged six months to five years. (more…)


Vitamin C in prevention of atrial fibrillation after coronary artery bypass graft: double blind randomized clinical trial

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Original Article

Tehran Univ Med J (TUMJ) 2014 March;71(12):787-93

Author Affiliations:
Mahmoodreza Sarzaeem M.D.1
Nasim Shayan M.A.2*

1- Department of Cardiovascular Surgery, Tehran University of Medical Sciences, Tehran, Iran.
2- Executive Director of Cardiac Surgery and Transplantation Research Center, Dr. Shariati Hospital, Tehran, Iran.

*Corresponding author: Cardiac Surgery and Transplantation Research Center, Dr. Shariati Hospital, North Karegar Ave., Tehran, Iran.
Tel: +98- 21- 88633037
E-mail: nsm_shayan@yahoo.com

Received: 04 Sep. 2013    Accepted: 07 Dec. 2013    Available online: 01 Feb. 2014

Abstract:
Background: Atrial fibrillation is the most common arrhythmia after cardiac surgery. Vitamin C as an antioxidant has an important role in reducing the incidence of postop-erative atrial fibrillation. The present study aimed at administrating vitamin C as a way to reduce the incidence of post-CABG atrial fibrillation. (more…)


Celecoxib versus prednisolone in medication overuse headache withdrawal treatment: double blind randomized clinical trial

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Original Article

Tehran Univ Med J (TUMJ) 2014 March;71(12):780-6

Author Affiliations:
Mansoureh Toghae M.D.1,2
Mohammad Reza Ghini M.D.1
Seyed Mohammad Hassan Pak-nejad M.D.2
Elahe Taghvaii Zahmat Kesh M.D.1
Tayeb Ramim M.D.3*

1- Department of Neurology, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran.
2- Iranian Center of Neurological Research, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran.
3- Sina Trauma and Surgery Research Center, Tehran University of Medical Sciences, Tehran, Iran.

*Corresponding author: Sina Hospital, Imam Khomeini Ave., Hassan Abad Sq., Tehran, Iran.
Tel: +98- 21- 66348529
E-mail: dr.tayebramim@gmail.com

Received: 18 Jun 2013    Accepted: 13 Nov. 2013    Available online: 01 Feb. 2014

Abstract:
Background: Many drugs have been abused by patients for headache management. Celecoxib has not been abuse widely as a pain relief drug for headache. The aim of this study was comparison between celecoxib and prednisolone in bridge stage therapy following medication overuse headache. (more…)


Central effects of synthesized dihydropyridine derivatives and nifedipine on systolic blood pressure and heart rate of rats

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Original Article

Tehran Univ Med J (TUMJ) 2014 March;71(12):773-9

Author Affiliations:
Azam Bakhtiarian Ph.D.1
Sattar Ostadhadi Ph.D. Candidate1
Masoumeh Jorjani Ph.D.2
Sepideh Hashempour M.Sc.3
Shahrbanoo Oryan Ph.D.4
Vahid Nikoui Ph.D. Candidate1*

1- Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
2- Department of Pharmacology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
3- Islamic Azad University, North Tehran Branch, Tehran, Iran.
4- Department of Biology, Science Faculty, Tarbiat Moallem University, Karaj, Iran.

*Corresponding author: Department of Pharmacology, School of Medicine,
Tehran University of Medical Sciences,
Poursina St., Qods St., Keshavarz Blvd.,
Tehran, Iran.
Tel: +98- 21- 64053215
E-mail: nikoui@razi.tums.ac.ir

Received: 16 July. 2013    Accepted: 25 Dec. 2013    Available online: 01 Feb. 2014

Abstract:
Background: Calcium channel blockers have an important role in treatment of various cardiovascular diseases including hypertension, angina pectoris and cardiac arrhythmias, so study of cardiovascular effects of derivatives of these drugs are useful. Nifedipine is one of these drugs that used widely to treat hypertension and other cardiovascular diseases. The aim of the present study was to evaluate the central effects of synthesized dihydropyridine derivatives on systolic blood pressure and heart rate of rats and comparison to nifedipine. (more…)


Changes in IL-6 and interferon gamma levels in induced varicocele in premature rats

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Original Article

Tehran Univ Med J (TUMJ) 2014 March;71(12):763-72

Author Affiliations:
Bahareh Habibi M.Sc.1
Behjat Seifi Ph.D.1
Hamidreza Sadeghipour Roudsari Ph.D1*
Ali Akbar Amir Zargar Ph.D2
Seyed Mohammad Hossain Noori Mugahi Ph.D.3

1- Department of Physiology, Tehran University of Medical Science, Tehran, Iran.
2- Department of Immunology, Tehran University of Medical Science, Tehran, Iran.
3- Department of Histology, Tehran University of Medical Science, Tehran, Iran.

*Corresponding author: Tehran University of Medical Sciences, Poursina St., Ghods Ave., Tehran. Iran.
Tel: +98- 21- 66419484
E-mail: b-seifi@tums.ac.ir

Received: 20 Nov. 2013    Accepted: 29 Dec. 2013    Available online: 01 Feb. 2014

Abstract:
Background: Varicocele is a dilated vein of the pampiniform plexus that cause to detrimental time-dependent effects so this study describes the effect of varicocele on the level of IL-6 and interferon gamma in serum and testis tissue, number of sertoli and spermatogonia cells, seminiferous tubules diameter and sperm activity in immature rats. (more…)


Microsatellite instability detection using BAT-25 and BAT-26 by Real Time PCR and HPLC in colorectal cancer

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Original Article

Tehran Univ Med J (TUMJ) 2014 March;71(12):753-62

Author Affiliations:
Marjan Rismanchi M.Sc.1,2
Pooneh Mokarram Ph.D.1,3,4*
Mahvash Alizadeh Naeeni M.D.3,5
Mahdi Paryan Ph.D.6
Zohreh Honardar B.Sc.1
Soudabeh Kavousipour M.Sc.1
Abbas Alipour M.D., Ph.D.7

1- Department of Biochemistry, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
2- Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
3- Gastroenterohepatology Research Center, Nemazee Hospital, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
4- Advanced Biomedical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
5- Department of Internal Medicine, School of Medicine, Shiraz University of Medical Sciences, Tehran, Iran.
6- Research and Development De-partment, Production and Research Complex Pasteur Institute, Tehran, Iran.
7- Department of Epidemiology, Medical Faculty, Mazandaran University of Medical Sciences, Mazandaran, Iran.

*Corresponding author: Department of Biochemistry, Gastroenterohepatology Research Center, Nemazee Hospital, School of Medicine, Shiraz University of Medical Sciences, Zand St., Shiraz, Iran.
Tel: +98- 711-2303029
E-mail: mokaram2@gmail.com

Received: 09 Sep. 2013    Accepted: 07 Dec. 2013    Available online: 01 Feb. 2014

Abstract:
Background: Colorectal Cancer (CRC) is the third common cancer in the world. One of the pathways in colorectal tumor genesis is Microsatellite Instability (MSI+). MSI is detected in about 15% of all colorectal cancers. Colorectal tumors with MSI have distinctive features compared with Microsatellite Stable (MSS) tumors. Due to the high percentage of MSI+ in patients with CRC in Iran, screening of this type of CRC is imperative. In current study, two markers (BAT-26 and BAT-25) were used to determine an appropriate screening technique with high sensitivity and specificity to diagnose MSI status in patients with CRC. (more…)


Table of Contents >> Tehran University Medical Journal (TUMJ), Volume 71, Number 11, February 2014

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Utilization of Lambda bacteriophage as an Apoptin effective delivery platform to the BT-474 human breast carcinoma
Ghaderi N, Esazadeh Kh, Shoae Hasani A.

Letrozole and misoprostol versus misoprostol alone for termination of pregnancy: a randomized clinical trial
Rezai Z, Heydari Bazardehi S.S, Ghasemi Nezhad A, Sadeghi A.S, Ghorbani Yekta B.

Delivered dose to scrotum in rectal cancer radiotherapy by thermoluminescence dosimetry comparing to dose calculated by planning software
Haddad P, Karimimoghaddam Zh, Farhan F, Esfahani M, Afkhami M, Amouzegar-Hashemi F.

Distal femoral varus osteotomy in 27 young patients with genu valgum
Jabalameli M, Bagheri Fard A, Jahansouz A, Mokhtari T.

Femoral malrotation following intramedullary nailing in 70 patients
Saberi S, Sobhani Eraghi A, Farzan M, Safar-Ali Farkhani H, Mardookhpour Sh,Mirzaaghapour M.

The relationship between cerebrospinal fluid C-reactive protein and neonatal meningitis
Khosravi N, Khalesi N, Noorbakhsh S, Javadinia Sh, Asgarian R, Tabatabai A.

The relationship between serum level of 25 OH-Vitamin D3 and severity of coronary artery disease
Zand Parsa A.F, Faryadras P, Esteghamati A, Gilani Larimi N.

Relationship between s alleles of vacA gene of Helicobacter pylori and gastroduodenal diseases in Iran: a brief report
Latifi-Navid S, Mohammadi Sh, Zahri S.

Mean sound level in operation rooms in a referral hospital:  a brief report
Joneidi Jafari A, Sahebdel E, Hajipour A, Jafari Javid M, Mireskandari S.M, Karvandian K, Jafarzadeh A, Samadi Sh.

Replantation of traumatic limb amputation above the elbow: a report of 4 cases
Karimian F, Ghaderi H, Aminian A, Haghighikian S.M, Mirjafari S.A.