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Table of Contents >> Tehran University Medical Journal (TUMJ), Volume 72, Number 9, December 2014

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Helicobacter pylori virulence genes and microevolution in host and the clinical outcome: review article
Bakhti S.Z, Latifi-Navid S, Zahri S.

Anesthesia residents’ training and start time delays in operating room
Husaain Khan Z, Alavi S.Sh, Arbabi Sh, Makarem J.

Evaluation of IL-17 gene expression in peripheral blood and sputum of asthma patients and healthy individuals
Yazdani R, Ganjalikhani Hakemi M, Sherkat R, Rezaei A, Farahani R, Beiranvand B.

Frequency determination of HLA-DRB1 and HLA-DQB1 alleles in children with primary vesicoureteral reflux
Bazrafshani M, Parvaresh S, Sadeghi Lotfabadi A, Hosseini F.

Radiographic changes of lumbar spine and pelvis in chronic spinal injury
Shariatpanahi Sh, Khodakarim S, Abolpour Mofrad F.

Intraoperative visualization, frozen section, and permanent pathology in endometrial cancer
Aminimoghaddam S, Mahmoudzadeh F, Maghsoudnia A, Ghaemmaghami F.

Risk factors of maternal mortality in Sistan region: 10-year report
Sarani M, Shahraki Z, Shirazi M, Saravani S.

Effectiveness of post-exposure rabies prophylaxis
Esmaeilzadeh F, Hatam N, Esmaeilzadeh Zh, Rajabi A, Anami M, Vahedi S, Mirzaei H.

Relationship of Helicobacter pylori vacA-i1 and -i2 alleles with gastric cancer risk, Iran: brief report
Mottaghi B, Safaralizadeh R, Jabbarpour Bonyadi M, Latifi-Navid S, Somi M.H, Mahdavi M.

Long-term results of open gastric bypass with Roux-en-Y method for morbid obesity: Brief report
Maddah Gh, Shabahang H, Barband M.R, Abdollahi A, Tavassoli A.


Long-term results of open gastric bypass with Roux-en-Y method for morbid obesity: brief report

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Brief Report

Tehran Univ Med J (TUMJ) 2014 December;72(9):643-7

Author Affiliations:
Ghodratolah Maddah M.D.1
Hossein Shabahang M.D.1
Mohammad Reza Barband M.D.2*
Abbas Abdollahi M.D.3
Alireza Tavassoli M.D.1

1- Department of General Surgery, Endoscopic and Minimally Invasive Surgery Research Center, Ghaem Hospital, Faculty of Medicine, Mashhad University of Medical  Sciences, Mashhad, Iran.
2- Department of General Surgery, Mashhad University of Medical   Sciences, Mashhad, Iran.
3- Department of Surgery, Surgical Oncology Research Center, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical   Sciences, Mashhad, Iran.

* Corresponding author: Department of Surgery, Ghaem Hospital, Mashhad, Iran.
Tel: +98-51-38012841
E-mail: mrbarband@yahoo.com

Received: 17 Aug. 2014    Accepted: 26 Oct. 2014    Available online: 11 Dec. 2014

Abstract:
Background: This study aims to evaluate the outcomes and late complications of open Roux-en-Y gastric bypass surgery in the treatment of morbid obesity. (more…)


Relationship of Helicobacter pylori vacA i1 and i2 alleles with gastric cancer risk, Iran: a brief report

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Brief Report

Tehran Univ Med J (TUMJ) 2014 December;72(9):638-642

Author Affiliations:
Batool Mottaghi M.Sc.1
Reza Safaralizadeh Ph.D.1*
Morteza Jabbarpour Bonyadi Ph.D.1
Saeid Latifi-Navid Ph.D.2
Mohammad Hossien Somi M.D.3
Majid Mahdavi Ph.D.1

1- Department of Biology, Faculty of Natural Sciences, University of Tabriz, Tabriz, Iran.
2- Department of Biology, Faculty of Sciences, University of  Mohaghegh Ardabili, Ardabil, Iran.
3- Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

* Corresponding author: Dept. of Animal Biology, Faculty of Natural Science, University of Tabriz, 29 Bahman Blvd., Tabriz, Iran.
Tel: +98-41-33392694
E-mail: safaralizadeh@tabrizu.ac.ir

Received: 16 Apr. 2014    Accepted: 27 Oct. 2014    Available online: 11 Dec. 2014

Abstract:
Background: Helicobacter pylori vacA (vacuolating toxin A) gene is comprised of mid- (m), intermediate- (i) and signal-regions. Recently, the vacA-i region genotype has been suggested to be a better predictor of disease severity than either the s- or m-region. The main aim of the present study was to determine the associations of i region polymorphisms of vacA gene with gastric cancer (GC) and peptic ulcer disease (PUD) in Azerbaijan Province patients. (more…)


Effectiveness of post-exposure rabies prophylaxis

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Original Article

Tehran Univ Med J (TUMJ) 2014 December;72(9):630-7

Author Affiliations:
Firooz Esmaeilzadeh Ph.D. Student1
Nahid Hatam Ph.D.2
Zhila Esmaeilzadeh Student3
Abdolhalim Rajabi Ph.D. Student4*
Meysam Anami M.Sc.5
Sajad Vahedi M.Sc.5
Hossien Mirzaei M.Sc. Student6

1- Department of Health Economics, Tehran University of Medical Sciences, Tehran, Iran.
2- Department of Health Service Administration, School of Management and Information Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
3- Department of Public Health, Maragheh University of Medical Sciences, Maragheh, Iran.
4- Department of Epidemiology, Iran University of Medical Sciences, Tehran, Iran.
5- Department of Health Economics, Shiraz University of Medical Sciences, Shiraz, Iran.
6- Department of Epidemiology,  Tehran University of Medical Sciences, Tehran, Iran.

* Corresponding author: Iran University of Medical Sciences, Next to the Milad Tower, Hemat Highway, Tehran, Iran.
Tel: +98-21-88622706
E-mail: rajabiepid@gmail.com

Received: 13 Aug. 2014    Accepted: 28 Oct. 2014    Available online: 11 Dec. 2014

Abstract:
Background: The rabies is a deadly disease and if its symptoms break out in a person, he will certainly die. However, the deaths caused rabies can be prevented by post-exposure prophylaxis (PEP). (more…)


Risk factors of maternal mortality in Sistan region: 10-year report

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Original Article

Tehran Univ Med J (TUMJ) 2014 December;72(9):623-9

Author Affiliations:
Mohammad Sarani M.Sc., MPH.1
Zahra Shahraki M.D.2
Mahboobeh Shirazi M.D.3*
Soleiman Saravani M.Sc.4

1- Faculty of Social Medicine, University of Zabol, Zabol, Iran.
2- Department of Maternal, Fetal and Neonatal, Obstetrics, Zabol University of Medical Sciences, Zabol, Iran.
3- Maternal, Fetal and Neonatal Research Center, Tehran University of Medical Sciences, Tehran, Iran.
4- Faculty of Social Medicine, University of Zabol, Zabol, Iran.

* Corresponding author: General Moheb Women Hospital (Mirza Koochak Khan Hospital), Ostad Nejatollahi St., Karim Khan Blvd., Tehran, Iran.
Tel: +98-21-88900002
E-mail: mahboobeh.shirazi@yahoo.in

Received: 23 Sep. 2014    Accepted: 28 Oct. 2014    Available online: 11 Dec. 2014

Abstract:
Background: Maternal mortality is one of the most important indicators of women health standard in developing countries. This study aimed to determine the prevalence of risk factors and etiology of maternal mortality in a geographic region of Iran. (more…)


Intraoperative visualization, frozen section, and permanent pathology in endometrial cancer

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Original Article

Tehran Univ Med J (TUMJ) 2014 December;72(9):617-22

Author Affiliations:
Soheila Aminimoghaddam M.D.1*
Fatemeh Mahmoudzadeh M.D. Student2
Andisheh Maghsoudnia M.Sc.3
Fatemeh Ghaemmaghami M.D.4

1- Department of Gynecology Oncology, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran.
2- Department of General Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
3- Department of Information Technology, Tarbiat Modares University, Tehran, Iran.
4- Department of Gynecology Oncology, Vali asr Hospital, Tehran University of Medical Sciences, Tehran, Iran.

* Corresponding author: Shariati St., Front of Sadr Bridge, Simiari Alley, Sadr Tower, First Floor, Tehran, Iran.
Postal code: 1931613683
Tel: +98-21-22211688
E-mail: dr_aminimoghaddam@yahoo.com

Received: 12 May 2014    Accepted: 05 Nov. 2014    Available online: 11 Dec. 2014

Abstract:
Background: Endometrial carcinoma is considered the most common gynecological cancer in the world. Pelvic and para-aortic lymphadenectomy is widely advised based on FIGO staging system. Intra-operative frozen sections analysis is used to identify patients at high risk for pelvic and para-aortic nodal metastasis evading lymphadenectomy in low-risk patients. However there is still some controversy concerning the efficiency of IFS. The aim of this study was to determine the validity and precision of frozen section diagnosis and gross examination of uterine specimen compared to the final histological results in patients with endometrial cancer. (more…)


Radiographic changes of lumbar spine and pelvis in chronic spinal injury

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Original Article

Tehran Univ Med J (TUMJ) 2014 December;72(9):608-16

Author Affiliations:
Shamsa Shariatpanahi M.D.1*
Soheila Khodakarim M.D.2
Fateme Abolpour Mofrad M.D.3

1- Department of Internal Medicine, Shahed University, Tehran, Iran.
2- Department of Biostatistics, Shahed University, Tehran, Iran.
3- Shahed University. Tehran, Iran.

* Corresponding author: Italia St., Mustafa Khomeini Hospital. Tehran, Iran.
Tel: +98-21-88963122
E-mail: shariat15@yahoo.com

Received: 31 May 2014    Accepted: 28 Oct. 2014    Available online: 11 Dec. 2014

Abstract:
Background: Chronic spinal cord injury has an important role in sensorimotor disorders which is associated with many complications and the rate of these complications should be certainly considered. The most important complications are the changes in bones and joints which come with pain and lead to increase in their motor disability. In this paper, the radiographic images were studied and the ossifications of spinal cord and pelvis were described and also the type of changes and their prevalence was evaluated. (more…)


Frequency determination of HLA-DRB1 and HLA-DQB1 alleles in children with primary vesicoureteral reflux

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Original Article

Tehran Univ Med J (TUMJ) 2014 December;72(9):601-7

Author Affiliations:
Mohammadreza Bazrafshani Ph.D.1*
Saeideh Parvaresh M.D.2
Ali Sadeghi Lotfabadi M.D.2
Fatemesadat Hosseini M.Sc.3

1- Department of Medical Genetics, Afzalipour School of Medicine and Physiology Research Center, Kerman University of Medical    Sciences, Kerman, Iran.
2- Department of Pediatrics, Afzalipour School of Medicine, Kerman University of Medical Sciences, Kerman, Iran.
3- Dr Mohammadreza Bazrafshani Medical Genetic laboratory, Kerman, Iran.

* Corresponding author: Department of Medical Genetics, Afzalipour School of Medicine, Kerman University of Medical Sciences, Kerman, Iran.
Tel: +98-34-32436880
E-mail: bazr61@yahoo.co.uk

Received: 10 May 2014    Accepted: 19 Nov. 2014    Available online: 11 Dec. 2014

Abstract:
Background: Vesicoureteral reflux (VUR) is the retrograde flow of urine from the bladder into the ureter and toward the kidney. Vesicoureteral reflux is the most common inherited disease in urogenital system. Primary VUR is the most common urological anomaly in children and it has been reported in 30-50% of those who present with urinary tract infection (UTI). The association of vesicoureteral reflux, urinary tract infection and renal damage is well known. ‍Current methods for vesicoureteral reflux diagnosis are unpleasant. Therefore, human leukocyte antigen system not only might help to detect causative gene but also would assists to establish better prognoses tests of this disease. In this study, the relationship between vesicoureteral reflux and HLA-DRB1 and HLA-DQB1 genes were investigated. (more…)


Evaluation of IL-17 gene expression in peripheral blood and sputum of asthma patients and healthy individuals

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Original Article

Tehran Univ Med J (TUMJ) 2014 December;72(9):595-600

Author Affiliations:
Reza Yazdani Ph.D. Student1
Mazdak Ganjalikhani Hakemi Ph.D.2*
Roya Sherkat M.D.3
Abbas Rezaei Ph.D.1
Rahim Farahani M.Sc.1
Behrouz Beiranvand M.Sc.  Student4

1- Department of Immunology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
2- Cellular and Molecular Immunology Research Center, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
3- Acquired Immunodeficiency  Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
4- Department of Biostatistics and Epidemiology, Kermanshah University of Medical Sciences, Kermanshah, Iran.

* Corresponding author: Cellular and Molecular Immunology Research Center, Isfahan University of Medical Sciences, Isfahan 81746-73461, Iran.
Tel: +98-31-3792-2482
E-mail: mghakemi@med.mui.ac.ir

Received: 26 Oct. 2014    Accepted: 25 Nov. 2014    Available online: 11 Dec. 2014

Abstract:
Background: Asthma as an airway disease is identified by increase network responsiveness of the trachea and bronchus to a specific stimulus. Th17 cells through production of IL-17 have important role in inflammation and autoimmune diseases .In some studies has been shown which IL-17 as major cytokine of Th17 probably has important role in the pathogenesis of allergy and asthma. (more…)


Anesthesia residents’ training and start time delays in operating room

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Original Article

Tehran Univ Med J (TUMJ) 2014 December;72(9):588-594

Author Affiliations:
Zahed Husaain Khan M.D.1
Seydeh Shohreh Alavi Ph.D.2
Shahriar Arbabi M.D.1
Jalil Makarem M.D.1*

1- Department of Anesthesiology and Intensive Care, Tehran University of Medical Sciences, Tehran, Iran.
2- Center for Research on Occupational Diseases, Tehran University of Medical Sciences, Tehran, Iran.

* Corresponding author: Imam Khomeini Hospital, Keshavarz Blvd., Tehran, Iran.
Tel: +98-21-61192828
E-mail: j-makarem@tums.ac.ir

Received: 10 Aug. 2014    Accepted: 29 Nov. 2014    Available online: 11 Dec. 2014

Abstract:
Background: Education is the main mission of teaching hospitals, but the residents’ learning in acquiring new techniques does interfere in the overall treatment process of patients. Studies pertaining to the effect of anesthesia residents’ training in operating room on treatment procedures have reported conflicting results. Therefore, this study was performed to investigate the effects of anesthesia residents’ training on start time operative delays. (more…)


Helicobacter pylori virulence genes and microevolution in host and the clinical outcome: review article

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Review Article

Tehran Univ Med J (TUMJ) 2014 December;72(9):575-87

Author Affiliations:
Seyedeh Zahra Bakhti M.Sc.
Saeid Latifi-Navid Ph.D.*
Saber Zahri Ph.D.

Department of Biology, Faculty of Sciences, University of Mohaghegh Ardabili, Ardabil, Iran.

* Corresponding author: Department of Biology, Faculty of Sciences, University of Mohaghegh Ardabili, Ardabil, Iran, Postal code: 1136756199
Tel: +98-21-22407088
E-mail: slatifin@yahoo.com

Received: 23 May 2014    Accepted: 27 Oct. 2014    Available online: 11 Dec. 2014

Abstract:
Helicobacter pylori (H. pylori) is the causative agent in development of gastroduodenal diseases, such as chronic atrophic gastritis, peptic ulcers, mucosa associated lymphoid tissue (MALT) lymphoma, and gastric cancer. H. pylori has been associated with inflammation in cardia, showing the fact that infection with this bacterium could also be a risk factor for gastric cardia cancer. Gastric cancer is the fourth most common cancer worldwide. This is the second leading cause of cancer-related deaths, and approximately 700,000 people succumb each year to gastric adenocarcinoma. It has been estimated that 69% of the Iranian population currently harbor H. pylori infection. The prevalence of duodenal ulcer and gastric cancer is high in Iranian populations. However, this has been largely influenced by geographic and/or ethnic origin. (more…)